Pratik Mukherjee, M.D., Ph.D.

Assistant Professor of Radiology and Bioengineering
Attending Neuroradiologist
pratik.mukherjee@radiology.ucsf.edu
(415) 353-9364

EDUCATION:

Yale UniversityB.A. 1988 Computer Science & Psychology, magna cum laude
Rockefeller UniversityPh.D. 1994 Computational Neuroscience
Cornell UniversityM.D. 1995 Medicine
  
Postgraduate Training 
Medicine InternshipNew York Hospital-Cornell Medical Center
Radiology ResidencyMallinckrodt Institute of Radiology, Washington University in St. Louis
Neuroradiology FellowshipMallinckrodt Institute of Radiology, Washington University in St. Louis

Positions and Honors:

Positions and Employment

2002-present   Assistant Professor of Radiology and Bioengineering, University of California, San Francisco

 

Other Experience and Professional Memberships

2002-present               Senior Member, American Society of Neuroradiology

2003-present               Member, American Society of Pediatric Neuroradiology

2002-present               Member, Organization for Human Brain Mapping

2004-present               Member, Society for Neuroscience

1998-present               Member, International Society for Magnetic Resonance in Medicine

1996-present               Member, Radiological Society of North America                                                       

2002-present               Peer Reviewer, American Journal of Neuroradiology                        

2002-present               Peer Reviewer, Journal of Computer Assisted Tomography            

2003-present               Ad Hoc Reviewer, JAMA                                                                                            

2003-present               Ad Hoc Reviewer, NeuroImage                                                                                 

2003-present               Ad Hoc Reviewer, Psychiatry Research

2003-present               Ad Hoc Reviewer, Pediatric Research

2005-present               Peer Reviewer, American Journal of Roentgenology                        

2005-present               Ad Hoc Reviewer, Annals of Neurology

2005-present               Ad Hoc Reviewer, Journal of Neuroscience

2006-present               Ad Hoc Reviewer, Magnetic Resonance in Medicine

2006-present               Ad Hoc Reviewer, Journal of Magnetic Resonance Imaging

2006-present               Ad Hoc Reviewer, Human Brain Mapping

 

                Honors and Awards:

2006                Outstanding Presentation Award in Functional Neuroradiology,

41st Annual Meeting of the American Society of Neuroradiology, San Diego, CA

2005                Berlex Best Paper Award in General Neuroradiology,

40th Annual Meeting of the American Society of Neuroradiology, Toronto, Canada

2004                Scholar Award in Neuroradiology Research, Neuroradiology Education and Research Foundation

2001                Berlex/ASNR Award in Basic Science Research, American Society of Neuroradiology

1999                Roentgen Resident/Fellow Research Award, Radiological Society of North America

1994                S. Koide Memorial Fellowship, Rockefeller University

1988-1995       Medical Scientist Training Program (MSTP) Grant, National Institutes of Health

 

B.   Selected peer-reviewed publications.

1.  Mukherjee P, Kaplan E.  The dynamics of neurons in the cat lateral geniculate nucleus: in vivo electrophysiology and computational modeling.  J Neurophysiol 1995; 74: 1222-1243.

2.  Levine MW, Cleland BG, Mukherjee P, Kaplan E.  Tailoring of variability in the lateral geniculate nucleus of the cat.  Biol Cybern 1996; 75: 219-227.

3.  Mukherjee P, Kaplan E.  Spectral analysis of the maintained discharge of cat lateral geniculate neurons.  Visual Neurosci 1998; 15: 529-539.

4.  Lin W, Mukherjee P, An H, Yu Y, Wang Y, Vo K, Lee BCP, Kido DK, Haacke EM.  Improving high-resolution MR BOLD venographic imaging using a T1 reducing contrast agent.  J Magn Reson Imaging 1999; 10: 118-123.

5.  Lee BCP, Vo KD, Kido DK, Mukherjee P, Reichenbach J, Lin W, Yoon M, Haacke EM.  Imaging of occult (low-flow) venous lesions using magnetic resonance high resolution BOLD venography.  AJNR Am J Neuroradiol 1999; 20:1239-1242.

6.  Mukherjee P, Bahn MM, McKinstry RC, Shimony JS, Cull TS, Akbudak E, Snyder AZ, Conturo TE.  Differences between gray matter and white matter water diffusion in stroke: diffusion-tensor MR imaging in 12 patients.  Radiology 2000; 215:211-220.

7.  Mukherjee P, McKinstry RC.  Reversible posterior leukoencephalopathy syndrome: evaluation with diffusion-tensor MR imaging.  Radiology 2001; 219:756-765.

8.  Gauvain KM, McKinstry RC, Mukherjee P, Perry A, Neil JJ, Kaufman BA, Hayashi RJ.  Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging.  AJR Am J Roentgenol 2001; 177:449-454.

9.  Mukherjee P, Miller JH, Shimony JS, Conturo TE, Lee BCP, Almli CR, McKinstry RC.  Normal brain maturation during childhood: developmental trends characterized with diffusion-tensor MR imaging.  Radiology 2001; 221:349-358.

10. Mukherjee P, Miller JH, Shimony JS, Philip JV, Nehra D, Snyder AZ, Conturo TE, Neil JJ, McKinstry RC.  Diffusion-tensor MR imaging of gray matter and white matter development during normal human maturation.  AJNR Am J Neuroradiol 2002; 23:1445-1456.

11. Mukherjee P, Kang HC, Videen TO, McKinstry RC, Powers WJ, Derdeyn C.  Cerebral blood flow in chronic carotid occlusive disease: comparison of dynamic susceptibility contrast perfusion magnetic resonance imaging with positron emission tomography.  AJNR Am J Neuroradiol 2003; 24:862-871.

12. Mazumdar A, Mukherjee P, Miller JH, Malde H, McKinstry RC.  Diffusion-weighted imaging of acute corticospinal tract injury preceding Wallerian degeneration in the maturing human brain.  AJNR Am J Neuroradiol 2003; 24:1057-1066.

13. Henry RG, Berman JI, Nagarajan SS, Mukherjee P, Berger MS.  Subcortical pathways serving cortical language sites: initial experience with diffusion tensor imaging fiber tracking combined with intraoperative language mapping.  NeuroImage 2004; 21:616-622.

14. Wintermark M, Fischbein NJ, Mukherjee P, Yuh EL, Dillon WP.  Unilateral putaminal CT, MR, and diffusion abnormalities secondary to nonketotic hyperglycemia in the setting of acute neurologic symptoms mimicking stroke.  AJNR Am J Neuroradiol 2004; 25:975-976.

15. Maas LC, Mukherjee P, Carballido-Gamio J, Veeraraghavan S, Miller SP, Partridge SC, Henry RG, Barkovich AJ, Vigneron DB.  Early laminar organization of the developing human cerebrum demonstrated with diffusion tensor imaging in extremely premature infants.  NeuroImage 2004; 22:1134-1140.

16. Partridge SC, Mukherjee P, Henry RG, Miller SP, Berman JI, Jin, H, Lu Y, Glenn OA, Ferriero DM, Barkovich AJ, Vigneron DB.  Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns.  NeuroImage 2004; 22:1302-1314.

17. Xu D Henry RG, Mukherjee P, Carvajal L, Miller SP, Barkovich AJ, Vigneron DB.  Single-shot fast spin-echo diffusion tensor imaging of the brain and spine with head and phased array coils at 1.5T and 3.0T.  Magn Reson Imaging 2004; 22:751-759.

18. Berman JI, Berger MS, Mukherjee P, Henry RG.  Diffusion tensor fiber tracking of the pyramidal tract from motor points defined by intraoperative cortical stimulation mapping of gliomas.  J Neurosurg 2004; 101:66-72.

19. Ojemann JG, McKinstry RC, Mukherjee P, Park TS, Burton H.  Hand somatosensory cortex activity following selective dorsal rhizotomy: report of three cases with fMRI.  Childs Nerv Syst 2005; 21:115-121.

20.     **Le TH, Mukherjee P, Henry RG, Berman JI, Ware M, Manley GT.  Diffusion tensor imaging and 3D fiber tractography of traumatic axonal shearing injury: an imaging correlate for the posterior callosal “disconnection” syndrome.  Neurosurgery 2005; 56:E195-E201.

21. **DeIpolyi AR, Mukherjee P, Gill KR, Henry RG, Partridge SC, Veeraraghavan S, Jin H, Lu Y, Miller SP, Ferriero DM, Vigneron DB, Barkovich AJ.  Comparing microstructural and macrostructural development of the cerebral cortex in premature newborns:  Diffusion tensor imaging versus cortical gyration.  Neuroimage 2005; 27:579-586.

22. Berman J, Mukherjee P, Partridge SC, Miller SP, Ferriero DM, Barkovich AJ, Vigneron DB, Henry RG.  Quantitative diffusion tensor MRI fiber tractography of sensorimotor white matter development in premature infants.  Neuroimage  2005; 27:862-871.

23. Partridge SC, Mukherjee P, Berman JI, Henry RG, Miller SP, Lu Y, Glenn OA, Ferriero DM, Barkovich AJ, Vigneron DB.  Tractography-based quantitation of diffusion tensor imaging parameters in white matter tracts of preterm newborns.  J Magn Reson Imaging 2005; 22:467-474.

24. Miller SP, Ferriero DM, Leonard C, Piecuch R, Glidden DV, Partridge JC, Perez M, Mukherjee P, Vigneron DB, Barkovich AJ.  Early brain injury in premature newborns detected with magnetic resonance imaging is associated with adverse early neurodevelopmental outcome.  J Pediatr 2005; 147:609-16.

25. Partridge SC, Vigneron DB, Charlton NN, Berman JI, Henry RG, Mukherjee P, McQuillen PS, Karl TR, Barkovich AJ, Miller SP.  Pyramidal tract maturation after brain injury in newborns with heart disease.  Ann Neurol 2006; 59:640-651.

26. Barkovich AJ, Miller SP, Bartha A, Newton N, Hamrick SE, Mukherjee P, Glenn OA, Xu D, Partridge JC, Ferriero DM, Vigneron DB.  MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy.  AJNR Am J Neuroradiol. 2006; 27:533-47.

27.     Hess CP, Mukherjee P, Han ET, Xu D, Vigneron DB.  Q-ball reconstruction of multimodal fiber orientations using the spherical harmonic basis.  Magn Reson Med 2006; 56:104-117.

28.     Chen JS, Mukherjee P, Dillon WP, Wintermark M.  Restricted diffusion in bilateral optic nerves and retinas as an indicator of venous ischemia caused by cavernous sinus thrombophlebitis.  AJNR Am J Neuroradiol 2006; 27:1815-1816.

29. Rodriguez-Carranza C, Mukherjee P, Vigneron D, Barkovich J, Studholme C.  A system for measuring regional surface folding of the neonatal brain from MRI.  Lecture Notes Computer Sci 2006; 4191:201-208.

30. Von Morze C, Tropp J, Banerjee S, Xu D, Karpodinis K, Carvajal L, Hess CP, Mukherjee P, Majumdar S, Vigneron DB.  An eight-channel nonoverlapping phased array coil with capacitative decoupling for parallel MRI at 3T.  Concepts in Magnetic Resonance Part B – Magnetic Resonance Engineering 2007; 31B: 37-43.

31. Niogi SN, Mukherjee P, McCandliss BD.  Diffusion tensor imaging segmentation of white matter structures using a Reproducible Objective Quantification Scheme (ROQS).  Neuroimage 2007; 35:166-74.

32. Mukherjee P, Hess CP, Xu D, Han ET, Kelley DA, Vigneron DB.  Development and initial evaluation of 7 Tesla q-ball imaging of the human brain.  Magn Reson Imaging 2007; in press.

 

NON-PEER REVIEWED PUBLICATIONS

 

                    REVIEW ARTICLES

 

Neil JJ, Miller JH, Mukherjee P, Huppi PS.  Diffusion tensor imaging of normal and injured developing human brain – a technical review.  NMR Biomed 2002; 15:543-552.

 

Miller JH, McKinstry RC, Philip JV, Mukherjee P, Neil JJ.  Diffusion tensor MR imaging of normal brain maturation: a guide to structural development and myelination.  AJR Am J Roentgenol 2003; 180:851-859.

 

Maas LC**, Mukherjee P.  Diffusion MRI: Overview and clinical applications in neuroradiology.  Applied Radiology 2005; 34:44-60.

 

Mukherjee P.  Diffusion tensor imaging and fiber tractography in acute stroke.  Neuroimaging Clin N Am 2005; 15:655-65.

 

Mukherjee P, McKinstry RC.  Diffusion tensor imaging and fiber tractography of human brain development.  Neuroimaging Clin N Am 2006; 16:19-43.

 

Hess CP, Mukherjee P.  Visualizing white matter pathways in the living human brain: Diffusion tensor imaging and beyond.  Neuroimaging Clin N Am 2007; in press.

 

Paul LK, Brown WS, Adolphs R, Tyszka JM, Richards LJ, Mukherjee P, Sherr EH.  Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity.  Nature Reviews Neurosci 2007; 8:287-99.

 

 

                      BOOKS

 

Mukherjee P (guest editor).  Advanced Pediatric Neuroimaging, An issue of the Neuroimaging Clinics, 16-1. Elsevier Saunders, 2006. ISBN: 1-4160-3532-X.

 

 

                      BOOK CHAPTERS

 

Kaplan E, Mukherjee P, Shapley RM.  Information filtering in the lateral geniculate nucleus.  In: Contrast Sensitivity (Eds. Lam D and Shapley RM), MIT Press, Cambridge, MA, 1993.

 

Barkovich AJ, Vigneron DB, Mukherjee P.  Physiological MR imaging of human brain development and developmental delay.  In: Physiological Magnetic Resonance Imaging in Clinical Neuroscience (Gillard J, Waldman A, Barker PB, eds.); Cambridge University Press; Cambridge, UK, 2004.

 

Mukherjee P, Henry RG.  Diffusion tensor imaging and tractography of the brain.  In: Clinical Magnetic Resonance Imaging, 3rd ed. (Edelman RR, Hesselink JR, Zlatkin MB, Crues JV, eds.); Elsevier; New York, NY, pp. 1616-1633, 2005.

 

 

                       LETTERS to the EDITOR

 

Mukherjee P, Bahn MM, McKinstry RC, Shimony JS, Akbudak E, Snyder AZ, Conturo TE.  Heterogeneity of apparent diffusion coefficients within infarcts. [letter]  Stroke 2001; 32:1695-1696.

 

Nakamura K, Mukherjee P, Swanson RA.  Vitamin B12 deficiency.  Arch Neurol 2004; 61:960.

 

 

ABSTRACTS (not yet appearing as full papers)

 

Awarded the 2006 Outstanding Presentation Award in Functional Neuroradiology:

Mukherjee P, Hess CP, Han ET, Xu D, Vigneron DB.  Whole brain high angular resolution diffusion imaging within a clinically feasible acquisition time.  Proceedings of the 41st Annual Meeting of the American Society of Neuroradiology.  San Diego: American Society of Neuroradiology, 2006.

 

Hess CP, Mukherjee P, Sherr EH.  High angular resolution diffusion imaging of interhemispheric connections in the normal human brain and in agenesis of the corpus callosum.  Proceedings of the 41st Annual Meeting of the American Society of Neuroradiology.  San Diego: American Society of Neuroradiology, 2006.

 

deIpolyi AR, Mukherjee P, Veeraraghavan S, Berman JI, Henry RG, Vigneron DB, Barkovich AJ.  Regional variation in human thalamic maturation revealed by diffusion tensor imaging of premature newborns.  Proceedings of the 41st Annual Meeting of the American Society of Neuroradiology.  San Diego: American Society of Neuroradiology, 2006.

 

Roberts DR, Mukherjee P.  Mapping cortical networks in human motor function using transcranial magnetic stimulation combined with diffusion tensor tractography.  Proceedings of the 41st Annual Meeting of the American Society of Neuroradiology.  San Diego: American Society of Neuroradiology, 2006.

 

Chung S, Mukherjee P, Henry RG, Berman JI, Hetts SW, Barkovich AJ, Sherr EH.  Corticocortical connectivity of Probst bundle fibers in callosal dysgenesis revealed by diffusion tensor imaging fiber tractography.  Proceedings of the Fourteenth Annual Meeting of the International Society for Magnetic Resonance in Medicine.  Seattle:  International Society for Magnetic Resonance in Medicine, 2006.

 

Hess CP, Mukherjee P, Han ET, Xu D, Vigneron DB.  Bootstrap comparison of the q-ball, spherical deconvolution and diffusion orientation transform methods for multimodal fiber orientation estimation from in vivo HARDI.  Proceedings of the Fourteenth Annual Meeting of the International Society for Magnetic Resonance in Medicine.  Seattle:  International Society for Magnetic Resonance in Medicine, 2006.

 

Berman JI, Mukherjee P, Hess CP, Han ET, Chung S, Henry RG.  Bootstrap tractography using multimodal fiber orientation data from high angular resolution diffusion imaging.  Proceedings of the Fourteenth Annual Meeting of the International Society for Magnetic Resonance in Medicine.  Seattle:  International Society for Magnetic Resonance in Medicine, 2006.

 

Awarded the 2007 Best Student Poster Award at the International Society for Magnetic Resonance in Medicine:

Chung S, Lee H, Veeraraghavan S, Xu D, Meeker M, Ghajar J, Manley GT, Henry RG, Mukherjee P.  Progressive white matter microstructural changes following traumatic brain injury revealed by bootstrap analysis of serial 3T diffusion tensor MRI.  Proceedings of the Fifteenth Annual Meeting of the International Society for Magnetic Resonance in Medicine.  Berlin, Germany:  International Society for Magnetic Resonance in Medicine, 2007.