Soonmee Cha, M.D.

scha picture
soonmee.cha@radiology.ucsf.edu
Telephone 415-353-1537/1668

INSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDY
(if applicable)
Georgetown University, Washington, DC B.S. 1983-1987 Chemistry
Georgetown University, Washington, DC M.D. 1987-1991 Medicine
Georgetown University Hospital, Washington, DC Internship 1991-1992 Transitional Internship
North Shore University Hospital, Manhasset, NY Residency 1992-1996 Diagnostic Radiology
New York University Medical Center, New York, NY Fellowship 1996-1998 Neuroradiology

A. Positions and Honors

Positions

1997-1998 Clinical Instructor of Neuroradiology,New York University Medical Center, New York, NY

1998-1999 Assistant Professor of Clinical Radiology, New York University School of Medicine

1999-2001 Assistant Professor of Radiology, New York University School of Medicine

2001-2005 Assistant Professor of Radiology and Neurological Surgery, University of California, San Francisco School of Medicine

2005-present Associate Professor of Radiology and Neurological Surgery, University of California, San Francisco School of Medicine

Certification

National Board of Medical Examiners (1991)

American Board of Radiology (1996)

Certificate of Added Qualification (CAQ) in Neuroradiology (1998)
 

Honors and Awards

 

· RSNA Certificate of Merit Award: Feinberg MJ, Cha S, Simon DW.

“A Biomechanical Approach to Understanding and Analyzing the Swallowing Response”. Scientific exhibit at the Radiological Society of North America, Chicago, IL, 1994.

· RSNA Certificate of Merit Award: Cha S, Simon D, Kalina P, et al.

“CT, MR and Angiographic Appearance of Unusual Posterior Fossa Lesions”. Scientific exhibit at the Radiological Society of North America, Chicago, IL, 1995.

· ASNR Outstanding Presentation Award in General Neuroradiology at the 38th Annual Meeting in Atlanta, GA, April 2000: Cha S, Pierce S, Knopp EA, et al.

“Dynamic Contrast-Enhanced T2*-Weighted Echo-Planar MR Imaging of Tumefactive Demyelinating Lesions”.

· ASNR Foundation Scholar Award in Neuroradiology Research for 2001. Cha S.

“Dynamic Contrast-enhanced T2*-weighted MRI and Histopathological Assessment of Experimental Gliomas”.

· Best Speaker Award, fMRI/DTI/PWI Morning Categorical Course: Cha, S.

International Society of Magnetic Resonance in Medicine, May 2006, Seattle, WA.

 

B. Selected peer-reviewed publications: (selected from 60 articles)

1. Knopp E, Cha S, Johnson G, et al. Glial neoplasms: Dynamic, contrast-enhanced T2•-weighted MR imaging. Radiology 1999; 211:791-798

2. Cha S, Lu S, Johnson G, Knopp EA. Dynamic susceptibility contrast MR imaging: Correlation of signal intensity changes with cerebral blood volume measurements.
J of Mag Res 2000;11:114-119

3. Cha S, Knopp EA, Johnson G, et al. Dynamic, contrast-enhanced T2•-weighted MR imaging of recurrent malignant gliomas treated with thalidomide and carboplatin. Amer
J Neuroradiol
2000;21:881-890

4. Cha S, Pierce S, Knopp EA, et al. Dynamic contrast-enhanced T2•-weighted MR imaging of tumefactive demyelinating lesions. Amer J Neuroradiol 2001;22:1109-1116

5. Yang S, Wetzel S, Law M, Zagzag D, Cha S•. Dynamic contrast-enhanced T2•-weighted MR imaging of gliomatosis cerebri. Am J Neuroradiol 2002;23:350-355

6. Law M, Cha S, Knopp EA, et al. Differentiation between primary high-grade gliomas and solitary metastasis using cerebral blood volume maps and proton MR
spectroscopic imaging. Radiology 2002; 222:715-721.

7. Wetzel SG, Cha S•, Johnson G, Lee P, Law M, Kasow DL, Pierce SD, Xue X. Relative cerebral blood volume measurements in intracranial mass lesions:
interobserver and intraobserver reproducibility study. Radiology 2002;224:797-803

8. Cha S, Knopp EA, Johnson G, et al. Dynamic contrast-enhanced susceptibility-weighted echo-planar Perfusion MR imaging of Intracranial Mass Lesions.
Radiology 2002;223:11-29.

9. Yang S, Wetzel S, Law M, Zagzag D, Cha S. Dynamic contrast-enhanced T2*-weighted MR imaging of gliomatosis cerebri. Amer J Neuroradiol 2002;23:350-355.

10. Lu S, Ahn D, Johnson G, Cha S. Peritumoral diffusion tensor imaging of primary and metastatic brain tumors. Amer J Neuroradiol 2003;24:937-941

11. Nelson SJ, Cha S. Imaging glioblastoma multiforme. Cancer J 2003;9:134-145

12. Cha S, Johnson G, Wadghiri YZ, Jin O, Babb J, Zagzag D, Turnbull DH. Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: Correlation with histopathology.
Magn Reson Med 2003;49:848-855

13. Cha S. Perfusion MR imaging: basic principles and clinical applications. Magn Reson Imaging Clin N Am 2003;11:403-413

14. Cha S, Tihan T, Crawford F, et al. Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurement derived
from dynamic susceptibility contrast enhanced MR imaging. Amer J Neuroradiol 2005;26:266-273

15. Lee MC, Chang SM, Cha S, Nelson SJ. Dynamic susceptibility contrast perfusion imaging radiation effects in normal appearing brain tissue: changes in the first-pass
and recirculation phases. J Magn Reson Imaging 2005;21:683-693

16. Smith J, Cha S, Mayo MC, McDermott MW, Parsa AT, Dillon WP, Berger MS. Serial diffusion-weighted MR imaging of gliomas: Distinguishing tumor recurrence from
post-resection injury. J Neurosurg 2005;103:428-438

17. Cha S, Yang L, Johnson G, Lai A, Chen M, Tihan T, Wendland M, Dillon WP. Comparison of microvascular permeability measurements, Ktrans, determined with
conventional steady-state T1-weighted and first-pass T2*-weighted MR imaging methods in gliomas and meningiomas. Amer J Neuroradiol 2006;27:409-417

18. Lee MC, Cha S, Chang S, Nelson SJ. Partial-volume model for determining white matter and gray matter cerebral blood volume for analysis of gliomas. J Magn Reson
Imaging
2006;23:257-266

19. Cha S. Update on brain tumor imaging: from anatomy to physiology. Amer J Neuroradiol 2006;27:475-487

20. Smith JS, Lin H, Mayo MC, Bannerjee A, Gupta N, Perry V, Cha S•. Diffusion-weighted MR imaging abnormalities in pediatric patients with surgically-treated intracranial
mass lesions. J Neurooncol. 2006 Sep;79(2):203-9.

21. Smith JS, Quinones-Hinojosa A, Phillips JJ, Bollen AW, McDermott MW, Cha S. Limitations of diffusion-weighted imaging in distinguishing between a brain tumor

and a central nervous system histoplasmoma. J Neurooncol. 2006 Sep;79(2):217-8.

 

C. Research Support.

Active Research Support

Award Category: Career Development Award Award Date: 8/1/2003-4/30/2008

Project Title: Brain tumor imaging: Quantitative MRI and 1H MRS.

Research Date: 07/01/2006 – 10/31/2007
Project Description: Phase II, multicenter, randomized, non-comparative clinical trial to evaluate the efficacy and safety of
bevacizumab alone or in combination with irinotecan for treatment of glioblastoma multiforme in first or second relapse.

 


Award Category: Career Development Award Brain Tumor SPORE
Project Title: Validation of neuroimaging biomarkers of gliomas using molecular and genetic analysis of image-guided tissue biopsy


Award Category: SPORE Project 3 Award Date: 7/1/02-6/30/07

Project Title: Prognostic value of MRSI parameters for patients with gliomas