Cheng Hong, MD

Assistant Professor
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Biography

Cheng William Hong, MD MS, is an Assistant Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Hong received an MD with special qualification in Biomedical Research from the Cleveland Clinic Lerner College of Medicine along with an MS in Biomedical Investigation from Case Western Reserve University.

Dr. Hong completed a diagnostic radiology residency in the T32 Clinician-Scientist Track at UCSD, where he received the RSNA Roentgen Resident Research Award and the UCSD Robert Mattrey, MD Research Award which recognizes outstanding research among graduating residents. Dr. Hong completed a Body MRI fellowship at Stanford and joined the UCSF faculty in 2022.

Dr. Hong has a special interest in liver imaging, and has been a part of the ACR LI-RADS Steering Committee since 2016. Dr. Hong’s research interests are noninvasive hepatic fat and iron quantification using MRI and ultrasound, and the clinical outcomes of LI-RADS.

Education

Fellowship, 2022 - Body MRI, Stanford University
Residency, 2021 - Radiology, University of California, San Diego
MD, 2015 - Medicine, Cleveland Clinic Lerner College of Medicine
MS, 2014 - Biomedical Investigation, Case Western Reserve University

Publications

Hong CW, Chernyak V, Choi JY, Lee S, Potu C, Delgado T, Wolfson T, Gamst A, Birnbaum J, Kampalath R, Lall C, Lee JT, Owen JW, Aguirre DA, Mendiratta-Lala M, Davenport MS, Masch W, Roudenko A, Lewis SC, Kierans AS, Hecht EM, Bashir MR, Brancatelli G, Douek ML, Ohliger MA, Tang A, Cerny M, Fung A, Costa EA, Corwin MT, McGahan JP, Kalb B, Elsayes KM, Surabhi VR, Blair K, Marks RM, Horvat N, Best S, Ash R, Ganesan K, Kagay CR, Kambadakone A, Wang J, Cruite I, Bijan B, Goodwin M, Cunha GM, Tamayo-Murillo D, Fowler KJ, Sirlin CB. Erratum for: A Multicenter Assessment of Interreader Reliability of LI-RADS Version 2018 for MRI and CT. Radiology. 2023 Jul; 308(1):e239018.
Hong CW, Chernyak V, Choi JY, Lee S, Potu C, Delgado T, Wolfson T, Gamst A, Birnbaum J, Kampalath R, Lall C, Lee JT, Owen JW, Aguirre DA, Mendiratta-Lala M, Davenport MS, Masch W, Roudenko A, Lewis SC, Kierans AS, Hecht EM, Bashir MR, Brancatelli G, Douek ML, Ohliger MA, Tang A, Cerny M, Fung A, Costa EA, Corwin MT, McGahan JP, Kalb B, Elsayes KM, Surabhi VR, Blair K, Marks RM, Horvat N, Best S, Ash R, Ganesan K, Kagay CR, Kambadakone A, Wang J, Cruite I, Bijan B, Goodwin M, Moura Cunha G, Tamayo-Murillo D, Fowler KJ, Sirlin CB. A Multicenter Assessment of Interreader Reliability of LI-RADS Version 2018 for MRI and CT. Radiology. 2023 06; 307(5):e222855.
Zhang YN, Fowler KJ, Boehringer AS, Montes V, Schlein AN, Covarrubias Y, Wolfson T, Hong CW, Valasek MA, Andre MP, Loomba R, Sirlin CB. Comparative diagnostic performance of ultrasound shear wave elastography and magnetic resonance elastography for classifying fibrosis stage in adults with biopsy-proven nonalcoholic fatty liver disease. Eur Radiol. 2022 Apr; 32(4):2457-2469.
Thura M, Sng JXE, Ang KH, Li J, Gupta A, Hong JM, Hong CW, Zeng Q. Targeting intra-viral conserved nucleocapsid (N) proteins as novel vaccines against SARS-CoVs. Biosci Rep. 2021 09 30; 41(9).
Hong CW, Cui JY, Batakis D, Xu Y, Wolfson T, Gamst AC, Schlein AN, Negrete LM, Middleton MS, Hamilton G, Loomba R, Schwimmer JB, Fowler KJ, Sirlin CB. Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. Abdom Radiol (NY). 2021 07; 46(7):3105-3116.
Hong CW, Hamilton G, Hooker C, Park CC, Tran CA, Henderson WC, Hooker JC, Fazeli Dehkordy S, Schwimmer JB, Reeder SB, Sirlin CB. Measurement of spleen fat on MRI-proton density fat fraction arises from reconstruction of noise. Abdom Radiol (NY). 2019 10; 44(10):3295-3303.
Hong CW, Park CC, Mamidipalli A, Hooker JC, Fazeli Dehkordy S, Igarashi S, Alhumayed M, Kono Y, Loomba R, Wolfson T, Gamst A, Murphy P, Sirlin CB. Longitudinal evolution of CT and MRI LI-RADS v2014 category 1, 2, 3, and 4 observations. Eur Radiol. 2019 Sep; 29(9):5073-5081.
Hooker JC, Hamilton G, Park CC, Liao S, Wolfson T, Dehkordy SF, Hong CW, Mamidipalli A, Gamst A, Loomba R, Sirlin CB. Inter-reader agreement of magnetic resonance imaging proton density fat fraction and its longitudinal change in a clinical trial of adults with nonalcoholic steatohepatitis. Abdom Radiol (NY). 2019 02; 44(2):482-492.
Hong CW, Marsh A, Wolfson T, Paige J, Dekhordy SF, Schlein AN, Housman E, Deiranieh LH, Li CQ, Wasnik AP, Jang HJ, Dietrich CF, Piscaglia F, Casola G, O'Boyle M, Richman KM, Valasek MA, Andre M, Loomba R, Sirlin CB. Reader agreement and accuracy of ultrasound features for hepatic steatosis. Abdom Radiol (NY). 2019 01; 44(1):54-64.
Fazeli Dehkordy S, Fowler KJ, Mamidipalli A, Wolfson T, Hong CW, Covarrubias Y, Hooker JC, Sy EZ, Schlein AN, Cui JY, Gamst AC, Hamilton G, Reeder SB, Sirlin CB. Hepatic steatosis and reduction in steatosis following bariatric weight loss surgery differs between segments and lobes. Eur Radiol. 2019 May; 29(5):2474-2480.
Fazeli Dehkordy S, Fowler KJ, Wolfson T, Igarashi S, Lamas Constantino CP, Hooker JC, Hong CW, Mamidipalli A, Gamst AC, Hemming A, Sirlin CB. Technical report: gadoxetate-disodium-enhanced 2D R2* mapping: a novel approach for assessing bile ducts in living donors. Abdom Radiol (NY). 2018 07; 43(7):1656-1660.
Kennedy P, Wagner M, Castéra L, Hong CW, Johnson CL, Sirlin CB, Taouli B. Quantitative Elastography Methods in Liver Disease: Current Evidence and Future Directions. Radiology. 2018 03; 286(3):738-763.
Hong CW, Fazeli Dehkordy S, Hooker JC, Hamilton G, Sirlin CB. Fat Quantification in the Abdomen. Top Magn Reson Imaging. 2017 Dec; 26(6):221-227.
Hong CW, Mamidipalli A, Hooker JC, Hamilton G, Wolfson T, Chen DH, Fazeli Dehkordy S, Middleton MS, Reeder SB, Loomba R, Sirlin CB. MRI proton density fat fraction is robust across the biologically plausible range of triglyceride spectra in adults with nonalcoholic steatohepatitis. J Magn Reson Imaging. 2018 04; 47(4):995-1002.
Hong CW, Wolfson T, Sy EZ, Schlein AN, Hooker JC, Fazeli Dehkordy S, Hamilton G, Reeder SB, Loomba R, Sirlin CB. Optimization of region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. J Magn Reson Imaging. 2018 04; 47(4):988-994.
Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB. Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2018 02; 47(2):418-424.
Thura M, Al-Aidaroos AQO, Yong WP, Kono K, Gupta A, Lin YB, Mimura K, Thiery JP, Goh BC, Tan P, Soo R, Hong CW, Wang L, Lin SJ, Chen E, Rha SY, Chung HC, Li J, Nandi S, Yuen HF, Zhang SD, Guan YK, So J, Zeng Q. PRL3-zumab, a first-in-class humanized antibody for cancer therapy. JCI Insight. 2016 06 16; 1(9):e87607.
Hong CW, Chow L, Turkbey EB, Lencioni R, Libutti SK, Wood BJ. Imaging Features of Radiofrequency Ablation with Heat-Deployed Liposomal Doxorubicin in Hepatic Tumors. Cardiovasc Intervent Radiol. 2016 Mar; 39(3):409-16.
Hong CW, Hsiao EC, Horvai AE, Link TM. Chronic recurrent multifocal osteomyelitis with an atypical presentation in an adult man. Skeletal Radiol. 2015 Sep; 44(9):1359-64.
Walton Diaz A, Shakir NA, George AK, Rais-Bahrami S, Turkbey B, Rothwax JT, Stamatakis L, Hong CW, Siddiqui MM, Okoro C, Raskolnikov D, Su D, Shih J, Han H, Parnes HL, Merino MJ, Simon RM, Wood BJ, Choyke PL, Pinto PA. Use of serial multiparametric magnetic resonance imaging in the management of patients with prostate cancer on active surveillance. Urol Oncol. 2015 May; 33(5):202.e1-202.e7.
Kwak JT, Hong CW, Pinto PA, Williams M, Xu S, Kruecker J, Yan P, Turkbey B, Choyke PL, Wood BJ. Is visual registration equivalent to semiautomated registration in prostate biopsy? Biomed Res Int. 2015; 2015:394742.
Hong CW, Reddy CA, Wilkinson DA, Klein EA, Ciezki JP. Influence of zonal dosimetry on prostate brachytherapy outcomes. J Contemp Brachytherapy. 2015 Feb; 7(1):17-22.
Hong CW, Rais-Bahrami S, Walton-Diaz A, Shakir N, Su D, George AK, Merino MJ, Turkbey B, Choyke PL, Wood BJ, Pinto PA. Comparison of magnetic resonance imaging and ultrasound (MRI-US) fusion-guided prostate biopsies obtained from axial and sagittal approaches. BJU Int. 2015 May; 115(5):772-9.
Hong CW, Walton-Diaz A, Rais-Bahrami S, Hoang AN, Türkbey B, Stamatakis L, Xu S, Amalou H, Siddiqui MM, Nix JW, Vourganti S, Merino MJ, Choyke PL, Wood BJ, Pinto PA. Imaging and pathology findings after an initial negative MRI-US fusion-guided and 12-core extended sextant prostate biopsy session. Diagn Interv Radiol. 2014 May-Jun; 20(3):234-8.
Hong CW, Amalou H, Xu S, Turkbey B, Yan P, Kruecker J, Pinto PA, Choyke PL, Wood BJ. Prostate biopsy for the interventional radiologist. J Vasc Interv Radiol. 2014 May; 25(5):675-84.
Hong CW, Zeng Q. Tapping the treasure of intracellular oncotargets with immunotherapy. FEBS Lett. 2014 Jan 21; 588(2):350-5.
Hong CW, Xu S, Imbesi KL, Wood BJ. Integrated laser-guided CT biopsy. Clin Imaging. 2013 Nov-Dec; 37(6):1135-7.
Park JE, Yuen HF, Zhou JB, Al-Aidaroos AQ, Guo K, Valk PJ, Zhang SD, Chng WJ, Hong CW, Mills K, Zeng Q. Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia. EMBO Mol Med. 2013 Sep; 5(9):1351-66.
Walton Diaz A, Hoang AN, Turkbey B, Hong CW, Truong H, Sterling T, Rais-Bahrami S, Siddiqui MM, Stamatakis L, Vourganti S, Nix J, Logan J, Harris C, Weintraub M, Chua C, Merino MJ, Choyke P, Wood BJ, Pinto PA. Can magnetic resonance-ultrasound fusion biopsy improve cancer detection in enlarged prostates? J Urol. 2013 Dec; 190(6):2020-2025.
Hong CW, Abi-Jaoudeh N, Wood BJ. Needle slippage from needle hub hardware during ablation. Cardiovasc Intervent Radiol. 2013 Oct; 36(5):1436-7.
Hong CW, Zeng Q. Awaiting a new era of cancer immunotherapy. Cancer Res. 2012 Aug 01; 72(15):3715-9.
Hong CW, Sinha-Roy A, Schoenfield L, McMahon JT, Dupps WJ. Collagenase-mediated tissue modeling of corneal ectasia and collagen cross-linking treatments. Invest Ophthalmol Vis Sci. 2012 Apr 30; 53(4):2321-7.
Guo K, Tang JP, Jie L, Al-Aidaroos AQ, Hong CW, Tan CP, Park JE, Varghese L, Feng Z, Zhou J, Chng WJ, Zeng Q. Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice. Oncotarget. 2012 Feb; 3(2):158-71.
Guo K, Li J, Tang JP, Tan CP, Hong CW, Al-Aidaroos AQ, Varghese L, Huang C, Zeng Q. Targeting intracellular oncoproteins with antibody therapy or vaccination. Sci Transl Med. 2011 Sep 07; 3(99):99ra85.