Kambiz Nael, MD

Professor In Residence

Biography

Biography

Kambiz Nael, MD, earned his medical degree from the Shiraz University Medical School in Shiraz, Iran, in 2000. He completed a diagnostic cardiovascular MRI post-doctoral fellowship at UCLA in 2006. After an internship in general surgery at Huntington Memorial Hospital in Pasadena, he completed a diagnostic radiology residency (2011) and a neuroradiology fellowship (2012) at UCLA’s David Geffen School of Medicine.

Dr. Nael has held faculty roles in neuroradiology and neuroscience at University of Arizona Medical Center (2012-15), the Icahn School of Medicine at Mount Sinai in New York City (2015-19), and David Geffen School of Medicine at UCLA (2020-2024). Dr. Nael’s leadership roles include Director of Neuroradiology MRI and Director of Stroke Imaging at University of Arizona, and Director of MRI, CT & Advanced Imaging and Director of Neuroimaging Advanced and Exploratory Lab at The Icahn School of Medicine.

Dr. Nael’s research investigates quantitative neuroimaging with a clinical focus on cerebrovascular diseases and stroke. Dr. Nael has developed quantitative models to estimate the infarct core in patients with acute stroke with the goal of reducing variability, and has presented his multidisciplinary research at national and international scientific meetings. Related research interests include developing advanced imaging technology and MR protocol design, which have resulted in a 6-minute MRI stroke protocol and a 4D parathyroid MR protocol. His work on using amplified MRI for coupled motion of the brain and blood flow was the winner of the American Society of Mechanical Engineers – Bioengineering Division Competition at the 2018 World Congress of Biomechanics, and the winner of the National Science Foundation (NSF) visualization challenge.

As an educator, Dr. Nael has designed and delivered multidisciplinary conferences for residents and fellows, and mentored medical students, post-docs, and junior faculty. He has published online education lectures on AI in neuroradiology and acute ischemic stroke, and is a frequently invited speaker at national and international society meetings. Dr. Nael is co-chair of the ASNR Research Committee, a member of the ASNR Educational Committee, and he has won the Radiology Editor’s Recognition Award with Distinction for four consecutive years.

Publications

Tavakkol E, Kihira S, McArthur M, Polson J, Zhang H, Arnold CW, Yoo B, Linetsky M, Salehi B, Ledbetter L, Kim C, Jahan R, Duckwiler G, Saver JL, Liebeskind DS, Nael K. Automated Assessment of the DWI-FLAIR Mismatch in Patients with Acute Ischemic Stroke: Added Value to Routine Clinical Practice. AJNR Am J Neuroradiol. 2024 Mar 28.
Salim H, Lakhani DA, Balar A, Musmar B, Adeeb N, Hoseinyazdi M, Luna L, Deng F, Hyson NZ, Mei J, Dmytriw AA, Guenego A, Faizy TD, Heit JJ, Albers GW, Urrutia VC, Llinas R, Marsh EB, Hillis AE, Nael K, Yedavalli V. Follow-up infarct volume on fluid attenuated inversion recovery (FLAIR) imaging in distal medium vessel occlusions: the role of cerebral blood volume index. J Neurol. 2024 Mar 20.
Yedavalli VS, Koneru M, Hoseinyazdi M, Greene C, Lakhani DA, Xu R, Luna LP, Caplan JM, Dmytriw AA, Guenego A, Heit JJ, Albers GW, Wintermark M, Gonzalez LF, Urrutia VC, Huang J, Nael K, Leigh R, Marsh EB, Hillis AE, Llinas RH. Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke. J Neurointerv Surg. 2024 Mar 12.
Lakhani DA, Balar AB, Koneru M, Wen S, Ozkara BB, Lu H, Wang R, Hoseinyazdi M, Mei J, Xu R, Nabi M, Mazumdar I, Cho A, Chen K, Sepehri S, Hyson N, Urrutia V, Luna L, Hillis AE, Heit JJ, Albers GW, Rai AT, Dmytriw AA, Faizy T, Wintermark M, Nael K, Yedavalli VS. The Relative Cerebral Blood Volume (rCBV) < 42% Is Independently Associated with Collateral Status in Anterior Circulation Large Vessel Occlusion. J Clin Med. 2024 Mar 10; 13(6).
Chien A, Tang H, Jagessar B, Chang KW, Peng N, Nael K, Salamon N. AI-Assisted Summarization of Radiologic Reports: Evaluating GPT3davinci, BARTcnn, LongT5booksum, LEDbooksum, LEDlegal, and LEDclinical. AJNR Am J Neuroradiol. 2024 Feb 07; 45(2):244-248.
Pionteck A, Abderezaei J, Fillingham P, Chuang YC, Sakai Y, Belani P, Rigney B, De Leacy R, Fifi JT, Chien A, Colby GP, Jahan R, Duckwiler G, Sayre J, Holdsworth SJ, Mossa-Basha M, Levitt MR, Mocco J, Kurt M, Nael K. Intracranial aneurysm wall displacement depicted by amplified Flow predicts growth. J Neurointerv Surg. 2024 Feb 06.
Mahmoudi K, Kim DH, Tavakkol E, Kihira S, Bauer A, Tsankova N, Khan F, Hormigo A, Yedavalli V, Nael K. Multiparametric Radiogenomic Model to Predict Survival in Patients with Glioblastoma. Cancers (Basel). 2024 Jan 30; 16(3).
McArthur MA, Tavakkol E, Bahr-Hosseini M, Jahan R, Duckwiler GR, Saver JL, Liebeskind DS, Nael K. Overestimation of ischemic core on baseline MRI in acute stroke. Interv Neuroradiol. 2024 Jan 23; 15910199231224500.
Yedavalli V, Koneru M, Hamam O, Hoseinyazdi M, Marsh EB, Llinas R, Urrutia V, Leigh R, Gonzalez F, Xu R, Caplan J, Huang J, Lu H, Wintermark M, Heit J, Guenego A, Albers G, Nael K, Hillis A. Pretreatment CTP Collateral Parameters Predict Good Outcomes in Successfully Recanalized Middle Cerebral Artery Distal Medium Vessel Occlusions. Clin Neuroradiol. 2023 Dec 28.
Koneru M, Hoseinyazdi M, Lakhani DA, Greene C, Copeland K, Wang R, Xu R, Luna L, Caplan JM, Dmytriw AA, Guenego A, Heit JJ, Albers GW, Wintermark M, Gonzalez LF, Urrutia VC, Huang J, Nael K, Leigh R, Marsh EB, Hillis AE, Llinas RH, Yedavalli VS. Redefining CT perfusion-based ischemic core estimates for the ghost core in early time window stroke. J Neuroimaging. 2023 Dec 25.
Koneru M, Hoseinyazdi M, Wang R, Ozkara BB, Hyson NZ, Marsh EB, Llinas RH, Urrutia VC, Leigh R, Gonzalez LF, Xu R, Caplan JM, Huang J, Lu H, Luna L, Wintermark M, Dmytriw AA, Guenego A, Albers GW, Heit JJ, Nael K, Hillis AE, Yedavalli VS. Pretreatment parameters associated with hemorrhagic transformation among successfully recanalized medium vessel occlusions. J Neurol. 2023 Dec 15.
Lakhani DA, Balar AB, Koneru M, Hoseinyazdi M, Hyson N, Cho A, Greene C, Xu R, Luna L, Caplan J, Dmytriw A, Guenego A, Wintermark M, Gonzalez F, Urrutia V, Huang J, Nael K, Rai AT, Albers GW, Heit JJ, Yedavalli V. Pretreatment CT perfusion collateral parameters correlate with penumbra salvage in middle cerebral artery occlusion. J Neuroimaging. 2024 Jan-Feb; 34(1):44-49.
Lakhani DA, Balar AB, Koneru M, Wen S, Hoseinyazdi M, Greene C, Xu R, Luna L, Caplan J, Dmytriw AA, Guenego A, Wintermark M, Gonzalez F, Urrutia V, Huang J, Nael K, Rai AT, Albers GW, Heit JJ, Yedavalli VS. The Compensation Index Is Better Associated with DSA ASITN Collateral Score Compared to the Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio. J Clin Med. 2023 Nov 28; 12(23).
Shahrouki P, Kihira S, Tavakkol E, Qiao JX, Vagal A, Khatri P, Bahr-Hosseini M, Colby GP, Jahan R, Duckwiler G, Szeder V, Ledbetter L, Cai S, Salehi B, Doshi AH, Belani P, Fifi JT, De Leacy R, Mocco J, Saver JL, Liebeskind DS, Nael K. Automated assessment of ischemic core on non-contrast computed tomography: a multicenter comparative analysis with CT perfusion. J Neurointerv Surg. 2023 Nov 02.
Ann P, Chen M, Naidich T, Belani P, Nael K. Arterial spin labeling perfusion in acute Wernicke encephalopathy: a case series discussion. BJR Case Rep. 2023 Nov; 9(6):20220137.
Tsui B, Chen IE, Nour M, Kihira S, Tavakkol E, Polson J, Zhang H, Qiao J, Bahr-Hosseini M, Arnold C, Tateshima S, Salamon N, Villablanca JP, Colby GP, Jahan R, Duckwiler G, Saver JL, Liebeskind DS, Nael K. Perfusion Collateral Index versus Hypoperfusion Intensity Ratio in Assessment of Collaterals in Patients with Acute Ischemic Stroke. AJNR Am J Neuroradiol. 2023 11; 44(11):1249-1255.
Yedavalli V, Kihira S, Shahrouki P, Hamam O, Tavakkol E, McArthur M, Qiao J, Johanna F, Doshi A, Vagal A, Khatri P, Srinivasan A, Chaudhary N, Bahr-Hosseini M, Colby GP, Nour M, Jahan R, Duckwiler G, Arnold C, Saver JL, Mocco J, Liebeskind DS, Nael K. CTP-based estimated ischemic core: A comparative multicenter study between Olea and RAPID software. J Stroke Cerebrovasc Dis. 2023 Nov; 32(11):107297.
Kobeissi H, Kallmes DF, Benson J, Nagelschneider A, Madhavan A, Messina SA, Schwartz K, Campeau N, Carr CM, Nasr DM, Braksick S, Scharf EL, Klaas J, Woodhead ZVJ, Harston G, Briggs J, Joly O, Gerry S, Kuhn AL, Kostas AA, Nael K, AbdalKader M, Kadirvel R, Brinjikji W. Impact of e-ASPECTS software on the performance of physicians compared to a consensus ground truth: a multi-reader, multi-case study. Front Neurol. 2023; 14:1221255.
Yedavalli V, Hamam O, Mohseni A, Chen K, Wang R, Heo HY, Heit J, Marsh EB, Llinas R, Urrutia V, Xu R, Gonzalez F, Albers G, Hillis A, Nael K. Pretreatment brain CT perfusion thresholds for predicting final infarct volume in distal medium vessel occlusions. J Neuroimaging. 2023 Nov-Dec; 33(6):968-975.
Bahr-Hosseini M, Nael K, Unal G, Iacoboni M, Liebeskind DS, Bikson M, Saver JL, TESSERACT Trial Group. High-definition Cathodal Direct Current Stimulation for Treatment of Acute Ischemic Stroke: A Randomized Clinical Trial. JAMA Netw Open. 2023 06 01; 6(6):e2319231.
Yildiz S, Schecht M, Aggarwal A, Nael K, Doshi A, Pawha PS. Diffusion Weighted Imaging in Spine Tumors. Neuroimaging Clin N Am. 2023 Aug; 33(3):459-475.
Kihira S, Derakhshani A, Leung M, Mahmoudi K, Bauer A, Zhang H, Polson J, Arnold C, Tsankova NM, Hormigo A, Salehi B, Pham N, Ellingson BM, Cloughesy TF, Nael K. Multi-Parametric Radiomic Model to Predict 1p/19q Co-Deletion in Patients with IDH-1 Mutant Glioma: Added Value to the T2-FLAIR Mismatch Sign. Cancers (Basel). 2023 Feb 07; 15(4).
Friedman JS, Jun T, Rashidipour O, Huang KL, Ellis E, Kadaba P, Belani P, Nael K, Tsankova NM, Sebra R, Hormigo A. Using EGFR amplification to stratify recurrent glioblastoma treated with immune checkpoint inhibitors. Cancer Immunol Immunother. 2023 Jun; 72(6):1893-1901.
Yedavalli VS, Hamam O, Gudenkauf J, Wang R, Llinas R, Marsh EB, Caplan J, Nael K, Urrutia V. Assessing the Efficacy of Mechanical Thrombectomy in Patients with an NIHSS < 6 Presenting with Proximal Middle Cerebral Artery Vessel Occlusion as Compared to Best Medical Management. Brain Sci. 2023 Jan 27; 13(2).
Chiu D, Qi J, Thin TH, Garcia-Barros M, Lee B, Hahn M, Mandeli J, Belani P, Nael K, Rashidipour O, Ghatan S, Hadjipanayis CG, Yong RL, Germano IM, Brody R, Tsankova NM, Gnjatic S, Kim-Schulze S, Hormigo A. A Phase I Trial of VEGF-A Inhibition Combined with PD-L1 Blockade for Recurrent Glioblastoma. Cancer Res Commun. 2023 01; 3(1):130-139.
Iutaka T, de Freitas MB, Omar SS, Scortegagna FA, Nael K, Nunes RH, Pacheco FT, Maia Júnior ACM, do Amaral LLF, da Rocha AJ. Arterial Spin Labeling: Techniques, Clinical Applications, and Interpretation. Radiographics. 2023 01; 43(1):e220088.
Chen IE, Tsui B, Zhang H, Qiao JX, Hsu W, Nour M, Salamon N, Ledbetter L, Polson J, Arnold C, BahrHossieni M, Jahan R, Duckwiler G, Saver J, Liebeskind D, Nael K. Automated estimation of ischemic core volume on noncontrast-enhanced CT via machine learning. Interv Neuroradiol. 2022 Dec 26; 15910199221145487.
Abayazeed AH, Abbassy A, Müeller M, Hill M, Qayati M, Mohamed S, Mekhaimar M, Raymond C, Dubey P, Nael K, Rohatgi S, Kapare V, Kulkarni A, Shiang T, Kumar A, Andratschke N, Willmann J, Brawanski A, De Jesus R, Tuna I, Fung SH, Landolfi JC, Ellingson BM, Reyes M. NS-HGlio: A generalizable and repeatable HGG segmentation and volumetric measurement AI algorithm for the longitudinal MRI assessment to inform RANO in trials and clinics. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdac184.
Kim WJ, Samarage HM, Zarrin D, Goel K, Wang AC, Johnson J, Nael K, Colby GP. Endovascular transmural access to carotid artery perivascular tissues: safety assessment of a novel technique. J Neurointerv Surg. 2023 Oct; 15(10):1007-1013.
Nael K. Eloquence-based Mismatch: Identifying Endovascular Therapy Responders in Acute Stroke. Radiology. 2023 Feb; 306(2):e222257.
Kihira S, Mei X, Mahmoudi K, Liu Z, Dogra S, Belani P, Tsankova N, Hormigo A, Fayad ZA, Doshi A, Nael K. U-Net Based Segmentation and Characterization of Gliomas. Cancers (Basel). 2022 Sep 14; 14(18).
Polson JS, Zhang H, Nael K, Salamon N, Yoo BY, El-Saden S, Starkman S, Kim N, Kang DW, Speier WF, Arnold CW. Identifying acute ischemic stroke patients within the thrombolytic treatment window using deep learning. J Neuroimaging. 2022 11; 32(6):1153-1160.
Chien A, Špiclin Ž, Bizjak Ž, Nael K. Computer-Assisted Aneurysm Growth Evaluation and Detection (AGED): Comparison with Clinical Aneurysm Follow-Up. J Blood Disord Transfus. 2022; 13(8).
Tsui B, Nour M, Chen I, Qiao JX, Salehi B, Yoo B, Colby GP, Salamon N, Villablanca P, Jahan R, Duckwiler G, Saver JL, Liebeskind DS, Nael K. MR Angiography in Assessment of Collaterals in Patients with Acute Ischemic Stroke: A Comparative Analysis with Digital Subtraction Angiography. Brain Sci. 2022 Sep 02; 12(9).
Yang HH, Sayre J, Dinh H, Nael K, Colby G, Wang A, Villablanca P, Salamon N, Chien A. Image-derived Metrics Quantifying Hemodynamic Instability Predicted Growth of Unruptured Intracranial Aneurysms. Stroke Vasc Interv Neurol. 2023 Jan; 3(1).
Shahrouki P, Gupta R, Belani P, Chien A, Doshi AH, De Leacy R, Fifi JT, Mocco J, Nael K. Differential Subsampling with Cartesian Ordering-MRA for Classifying Residual Treated Aneurysms. AJNR Am J Neuroradiol. 2022 06; 43(6):887-892.
Nael K, Sakai Y, Larson J, Goldstein J, Deutsch J, Awad AJ, Pawha P, Aggarwal A, Fifi J, Deleacy R, Yaniv G, Wintermark M, Liebeskind DS, Shoirah H, Mocco J. CT Perfusion collateral index in assessment of collaterals in acute ischemic stroke with delayed presentation: Comparison to single phase CTA. J Neuroradiol. 2022 Mar; 49(2):198-204.
Polson J, Zhang H, Nael K, Salamon N, Yoo B, Kim N, Kang DW, Speier W, Arnold CW. A Semi-Supervised Learning Framework to Leverage Proxy Information for Stroke MRI Analysis. Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:2258-2261.
Ghosh S, Azzi J, Chan AM, Nael K, Renteria AS, Steinberg A, Petersen BE. Primary Extranodal NK/T-Cell Lymphoma Presenting as Neurolymphomatosis Involving Multiple Cranial Nerves: A Case Report. Acta Haematol. 2022; 145(1):97-105.
De Leacy R, Bageac DV, Manna S, Gershon BS, Kirke D, Shigematsu T, Sinclair C, Chada D, Som P, Doshi A, Nael K, Berenstein A. A Radiologic Grading System for Assessing the Radiographic Outcome of Treatment in Lymphatic and Lymphatic-Venous Malformations of the Head and Neck. AJNR Am J Neuroradiol. 2021 10; 42(10):1859-1864.
Zhang H, Polson J, Nael K, Salamon N, Yoo B, Speier W, Arnold C. A Machine Learning Approach to Predict Acute Ischemic Stroke Thrombectomy Reperfusion using Discriminative MR Image Features. IEEE EMBS Int Conf Biomed Health Inform. 2021 Jul; 2021.
Nael K, Yoo B, Salamon N, Liebeskind DS. Acute Ischemic Stroke: MR Imaging-Based Paradigms. Neuroimaging Clin N Am. 2021 May; 31(2):177-192.
Zhang H, Polson JS, Nael K, Salamon N, Yoo B, El-Saden S, Scalzo F, Speier W, Arnold CW. Intra-domain task-adaptive transfer learning to determine acute ischemic stroke onset time. Comput Med Imaging Graph. 2021 06; 90:101926.
Kihira S, Tsankova NM, Bauer A, Sakai Y, Mahmoudi K, Zubizarreta N, Houldsworth J, Khan F, Salamon N, Hormigo A, Nael K. Multiparametric MRI texture analysis in prediction of glioma biomarker status: added value of MR diffusion. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab051.
Nael K, Gibson E, Yang C, Ceccaldi P, Yoo Y, Das J, Doshi A, Georgescu B, Janardhanan N, Odry B, Nadar M, Bush M, Re TJ, Huwer S, Josan S, von Busch H, Meyer H, Mendelson D, Drayer BP, Comaniciu D, Fayad ZA. Automated detection of critical findings in multi-parametric brain MRI using a system of 3D neural networks. Sci Rep. 2021 03 25; 11(1):6876.
Kihira S, Arnold AC, Pawha PS, Villablanca P, Nael K. Trans-synaptic degeneration of the optic radiation from optic nerve atrophy. Radiol Case Rep. 2021 Apr; 16(4):855-857.
Lu PJ, Yoo Y, Rahmanzadeh R, Galbusera R, Weigel M, Ceccaldi P, Nguyen TD, Spincemaille P, Wang Y, Daducci A, La Rosa F, Bach Cuadra M, Sandkühler R, Nael K, Doshi A, Fayad ZA, Kuhle J, Kappos L, Odry B, Cattin P, Gibson E, Granziera C. GAMER MRI: Gated-attention mechanism ranking of multi-contrast MRI in brain pathology. Neuroimage Clin. 2021; 29:102522.
Abderezaei J, Martinez J, Terem I, Fabris G, Pionteck A, Yang Y, Holdsworth SJ, Nael K, Kurt M. Amplified Flow Imaging (aFlow): A Novel MRI-Based Tool to Unravel the Coupled Dynamics Between the Human Brain and Cerebrovasculature. IEEE Trans Med Imaging. 2020 12; 39(12):4113-4123.
Song J, Kadaba P, Kravitz A, Hormigo A, Friedman J, Belani P, Hadjipanayis C, Ellingson BM, Nael K. Multiparametric MRI for early identification of therapeutic response in recurrent glioblastoma treated with immune checkpoint inhibitors. Neuro Oncol. 2020 11 26; 22(11):1658-1666.
Nael K, Pawha PS, Fleysher L, George K, Stueben J, Roas-Loeffler M, Delman BN, Fayad ZA. Prospective Motion Correction for Brain MRI Using an External Tracking System. J Neuroimaging. 2021 01; 31(1):57-61.
Sakai Y, Yang C, Kihira S, Tsankova N, Khan F, Hormigo A, Lai A, Cloughesy T, Nael K. MRI Radiomic Features to Predict IDH1 Mutation Status in Gliomas: A Machine Learning Approach using Gradient Tree Boosting. Int J Mol Sci. 2020 Oct 27; 21(21).
Nael K, Dagher JC, Downs ME, Fine MS, Brokaw E, Millward D. Maximum AmbiGuity Distance for Phase Imaging in Detection of Traumatic Cerebral Microbleeds: An Improvement over Current Imaging Practice. AJNR Am J Neuroradiol. 2020 11; 41(11):2027-2033.
Belani P, Kihira S, Pacheco F, Pawha P, Cruciata G, Nael K. Addition of arterial spin-labelled MR perfusion to conventional brain MRI: clinical experience in a retrospective cohort study. BMJ Open. 2020 06 11; 10(6):e036785.
Baron RB, Lakomkin N, Schupper AJ, Nistal D, Nael K, Price G, Hadjipanayis CG. Postoperative outcomes following glioblastoma resection using a robot-assisted digital surgical exoscope: a case series. J Neurooncol. 2020 Jul; 148(3):519-527.
Puig J, Biarnes C, Pedraza S, Vilanova JC, Pamplona R, Fernández-Real JM, Brugada R, Ramos R, Coll-de-Tuero G, Calvo-Perxas L, Serena J, Ramió-Torrentà L, Gich J, Gallart L, Portero-Otin M, Alberich-Bayarri A, Jimenez-Pastor A, Camacho-Ramos E, Mayneris-Perxachs J, Pineda V, Font R, Prats-Puig A, Gacto ML, Deco G, Escrichs A, Clotet B, Paredes R, Negredo E, Triaire B, Rodríguez M, Heredia-Escámez A, Coronado R, de Graaf W, Prevost V, Mitulescu A, Daunis-I-Estadella P, Thió-Henestrosa S, Miralles F, Ribas-Ripoll V, Puig-Domingo M, Essig M, Figley CR, Figley TD, Albensi B, Ashraf A, Reiber JHC, Schifitto G, Md Nasir U, Leiva-Salinas C, Wintermark M, Nael K, Vilalta-Franch J, Barretina J, Garre-Olmo J. The Aging Imageomics Study: rationale, design and baseline characteristics of the study population. Mech Ageing Dev. 2020 07; 189:111257.
Nael K. Reply. AJNR Am J Neuroradiol. 2020 05; 41(5):E29.
Restrepo P, Yong R, Laface I, Tsankova N, Nael K, Akturk G, Sebra R, Gnjatic S, Hormigo A, Losic B. Tumoral and immune heterogeneity in an anti-PD-1-responsive glioblastoma: a case study. Cold Spring Harb Mol Case Stud. 2020 04; 6(2).
Becker JL, Patel V, Johnson KJ, Guerrero M, Klein RR, Ranvier GF, Owen RP, Pawha P, Nael K. 4D-Dynamic Contrast-Enhanced MRI for Preoperative Localization in Patients with Primary Hyperparathyroidism. AJNR Am J Neuroradiol. 2020 03; 41(3):522-528.
Hao Q, Tsankova NM, Shoirah H, Kellner CP, Nael K. Vessel Wall MRI Enhancement in Noninflammatory Cerebral Amyloid Angiopathy. AJNR Am J Neuroradiol. 2020 03; 41(3):446-448.
Puig J, Shankar J, Liebeskind D, Terceño M, Nael K, Demchuk AM, Menon B, Dowlatshahi D, Leiva-Salinas C, Wintermark M, Thomalla G, Silva Y, Serena J, Pedraza S, Essig M. From "Time is Brain" to "Imaging is Brain": A Paradigm Shift in the Management of Acute Ischemic Stroke. J Neuroimaging. 2020 09; 30(5):562-571.
Nael K. Detection of Acute Infarction on Non-Contrast-enhanced CT: Closing the Gap with MRI via Machine Learning. Radiology. 2020 Mar; 294(3):645-646.
Sundaram VK, Goldstein J, Wheelwright D, Aggarwal A, Pawha PS, Doshi A, Fifi JT, Leacy R, Mocco J, Puig J, Nael K. Automated ASPECTS in Acute Ischemic Stroke: A Comparative Analysis with CT Perfusion. AJNR Am J Neuroradiol. 2019 12; 40(12):2033-2038.
Nael K, Drummond J, Costa AB, De Leacy RA, Fung MM, Mocco J. Differential Subsampling with Cartesian Ordering for Ultrafast High-Resolution MRA in the Assessment of Intracranial Aneurysms. J Neuroimaging. 2020 01; 30(1):40-44.
Vagal A, Wintermark M, Nael K, Bivard A, Parsons M, Grossman AW, Khatri P. Automated CT perfusion imaging for acute ischemic stroke: Pearls and pitfalls for real-world use. Neurology. 2019 11 12; 93(20):888-898.
Nael K, Sakai Y, Khatri P, Prestigiacomo CJ, Puig J, Vagal A. Imaging-based Selection for Endovascular Treatment in Stroke. Radiographics. 2019 10; 39(6):1696-1713.
Nael K, Tadayon E, Wheelwright D, Metry A, Fifi JT, Tuhrim S, De Leacy RA, Doshi AH, Chang HL, Mocco J. Defining Ischemic Core in Acute Ischemic Stroke Using CT Perfusion: A Multiparametric Bayesian-Based Model. AJNR Am J Neuroradiol. 2019 09; 40(9):1491-1497.
Swinburne NC, Schefflein J, Sakai Y, Oermann EK, Titano JJ, Chen I, Tadayon S, Aggarwal A, Doshi A, Nael K. Machine learning for semi-automated classification of glioblastoma, brain metastasis and central nervous system lymphoma using magnetic resonance advanced imaging. Ann Transl Med. 2019 Jun; 7(11):232.
Ahmed SU, Mocco J, Zhang X, Kelly M, Doshi A, Nael K, De Leacy R. MRA versus DSA for the follow-up imaging of intracranial aneurysms treated using endovascular techniques: a meta-analysis. J Neurointerv Surg. 2019 Oct; 11(10):1009-1014.
Puig J, Blasco G, Terceño M, Daunis-I-Estadella P, Schlaug G, Hernandez-Perez M, Cuba V, Carbó G, Serena J, Essig M, Figley CR, Nael K, Leiva-Salinas C, Pedraza S, Silva Y. Predicting Motor Outcome in Acute Intracerebral Hemorrhage. AJNR Am J Neuroradiol. 2019 05; 40(5):769-775.
Puig J, Biarnés C, Daunis-I-Estadella P, Blasco G, Gimeno A, Essig M, Balaña C, Alberich-Bayarri A, Jimenez-Pastor A, Camacho E, Thio-Henestrosa S, Capellades J, Sanchez-Gonzalez J, Navas-Martí M, Domenech-Ximenos B, Del Barco S, Puigdemont M, Leiva-Salinas C, Wintermark M, Nael K, Jain R, Pedraza S. Macrovascular Networks on Contrast-Enhanced Magnetic Resonance Imaging Improves Survival Prediction in Newly Diagnosed Glioblastoma. Cancers (Basel). 2019 Jan 14; 11(1).
Gibbs WN, Nael K, Doshi AH, Tanenbaum LN. Spine Oncology: Imaging and Intervention. Radiol Clin North Am. 2019 Mar; 57(2):377-395.
Pacheco FT, Nael K, Pawha PS. Intrasellar herniation: A newly described variant of downward central herniation. Neurology. 2018 11 06; 91(19):889-890.
Sakai Y, Delman BN, Fifi JT, Tuhrim S, Wheelwright D, Doshi AH, Mocco J, Nael K. Estimation of Ischemic Core Volume Using Computed Tomographic Perfusion. Stroke. 2018 10; 49(10):2345-2352.
Puig J, Blasco G, Alberich-Bayarri A, Schlaug G, Deco G, Biarnes C, Navas-Martí M, Rivero M, Gich J, Figueras J, Torres C, Daunis-I-Estadella P, Oramas-Requejo CL, Serena J, Stinear CM, Kuceyeski A, Soriano-Mas C, Thomalla G, Essig M, Figley CR, Menon B, Demchuk A, Nael K, Wintermark M, Liebeskind DS, Pedraza S. Resting-State Functional Connectivity Magnetic Resonance Imaging and Outcome After Acute Stroke. Stroke. 2018 10; 49(10):2353-2360.
Knitter JR, Erly WK, Stea BD, Lemole GM, Germano IM, Doshi AH, Nael K. Interval Change in Diffusion and Perfusion MRI Parameters for the Assessment of Pseudoprogression in Cerebral Metastases Treated With Stereotactic Radiation. AJR Am J Roentgenol. 2018 Jul; 211(1):168-175.
Chen IE, Swinburne N, Tsankova NM, Hefti MM, Aggarwal A, Doshi AH, Hormigo A, Delman BN, Nael K. Sequential Apparent Diffusion Coefficient for Assessment of Tumor Progression in Patients with Low-Grade Glioma. AJNR Am J Neuroradiol. 2018 06; 39(6):1039-1046.
Nael K, Doshi A, De Leacy R, Puig J, Castellanos M, Bederson J, Naidich TP, Mocco J, Wintermark M. MR Perfusion to Determine the Status of Collaterals in Patients with Acute Ischemic Stroke: A Look Beyond Time Maps. AJNR Am J Neuroradiol. 2018 Feb; 39(2):219-225.
Puig J, Blasco G, Daunis-I-Estadella P, van Eendendburg C, Carrillo-García M, Aboud C, Hernández-Pérez M, Serena J, Biarnés C, Nael K, Liebeskind DS, Thomalla G, Menon BK, Demchuk A, Wintermark M, Pedraza S, Castellanos M. High-permeability region size on perfusion CT predicts hemorrhagic transformation after intravenous thrombolysis in stroke. PLoS One. 2017; 12(11):e0188238.
Nael K, Bauer AH, Hormigo A, Lemole M, Germano IM, Puig J, Stea B. Multiparametric MRI for Differentiation of Radiation Necrosis From Recurrent Tumor in Patients With Treated Glioblastoma. AJR Am J Roentgenol. 2018 Jan; 210(1):18-23.
Reinertsen E, Neill SG, Nael K, Brat DJ, Hadjipanayis CG. Meningioma With Tyrosine-Rich Crystalloids: A Case Report and Review of the Literature. Int J Surg Pathol. 2018 Apr; 26(2):157-160.
Chartrain AG, Kurt M, Yao A, Feng R, Nael K, Mocco J, Bederson JB, Balchandani P, Shrivastava RK. Utility of preoperative meningioma consistency measurement with magnetic resonance elastography (MRE): a review. Neurosurg Rev. 2019 Mar; 42(1):1-7.
Puig J, Blasco G, Schlaug G, Stinear CM, Daunis-I-Estadella P, Biarnes C, Figueras J, Serena J, Hernández-Pérez M, Alberich-Bayarri A, Castellanos M, Liebeskind DS, Demchuk AM, Menon BK, Thomalla G, Nael K, Wintermark M, Pedraza S. Diffusion tensor imaging as a prognostic biomarker for motor recovery and rehabilitation after stroke. Neuroradiology. 2017 Apr; 59(4):343-351.
Nael K, Knitter JR, Jahan R, Gornbein J, Ajani Z, Feng L, Meyer BC, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Liebeskind DS, Guzy J, Starkman S, Saver JL, Kidwell CS. Multiparametric Magnetic Resonance Imaging for Prediction of Parenchymal Hemorrhage in Acute Ischemic Stroke After Reperfusion Therapy. Stroke. 2017 03; 48(3):664-670.
Munuera J, Blasco G, Hernández-Pérez M, Daunis-I-Estadella P, Dávalos A, Liebeskind DS, Wintermark M, Demchuk A, Menon BK, Thomalla G, Nael K, Pedraza S, Puig J. Venous imaging-based biomarkers in acute ischaemic stroke. J Neurol Neurosurg Psychiatry. 2017 Jan; 88(1):62-69.
Puig J, Sánchez-González J, Blasco G, Daunis-I-Estadella P, Federau C, Alberich-Bayarri Á, Biarnes C, Nael K, Essig M, Jain R, Wintermark M, Pedraza S. Intravoxel Incoherent Motion Metrics as Potential Biomarkers for Survival in Glioblastoma. PLoS One. 2016; 11(7):e0158887.
Erly WK, Becker JL, Inampudi R, Hur SJ, Nael K, Kubal WS. Fractures of the posterolateral maxillary sinus: a masticator space blowout injury? Emerg Radiol. 2016 Oct; 23(5):439-42.
Dagher J, Nael K. MR phase imaging with bipolar acquisition. NMR Biomed. 2017 Apr; 30(4).
Grams RW, Kidwell CS, Doshi AH, Drake K, Becker J, Coull BM, Nael K. Tissue-Negative Transient Ischemic Attack: Is There a Role for Perfusion MRI? AJR Am J Roentgenol. 2016 Jul; 207(1):157-62.
Nael K, Kubal W. Magnetic Resonance Imaging of Acute Stroke. Magn Reson Imaging Clin N Am. 2016 May; 24(2):293-304.
Nael A, Walavalkar V, Wu W, Nael K, Kim R, Rezk S, Zhao X. CD4-Positive T-Cell Primary Central Nervous System Lymphoma in an HIV Positive Patient. Am J Clin Pathol. 2016 Feb; 145(2):258-65.
Nael K, Hur J, Bauer A, Khan R, Sepahdari A, Inampudi R, Guerrero M. Dynamic 4D MRI for Characterization of Parathyroid Adenomas: Multiparametric Analysis. AJNR Am J Neuroradiol. 2015 Nov; 36(11):2147-52.
Dagher J, Nael K. MAGPI: A framework for maximum likelihood MR phase imaging using multiple receive coils. Magn Reson Med. 2016 Mar; 75(3):1218-31.
Bauer AH, Erly W, Moser FG, Maya M, Nael K. Differentiation of solitary brain metastasis from glioblastoma multiforme: a predictive multiparametric approach using combined MR diffusion and perfusion. Neuroradiology. 2015 Jul; 57(7):697-703.
Nael K, Trouard TP, Lafleur SR, Krupinski EA, Salamon N, Kidwell CS. White matter ischemic changes in hyperacute ischemic stroke: voxel-based analysis using diffusion tensor imaging and MR perfusion. Stroke. 2015 Feb; 46(2):413-8.
Nael K, Mossadeghi B, Boutelier T, Kubal W, Krupinski EA, Dagher J, Villablanca JP. Bayesian estimation of cerebral perfusion using reduced-contrast-dose dynamic susceptibility contrast perfusion at 3T. AJNR Am J Neuroradiol. 2015 Apr; 36(4):710-8.
Nael A, Siaghani P, Wu WW, Nael K, Shane L, Romansky SG. Metastatic malignant ectomesenchymoma initially presenting as a pelvic mass: report of a case and review of literature. Case Rep Pediatr. 2014; 2014:792925.
Nael K, Khan R, Choudhary G, Meshksar A, Villablanca P, Tay J, Drake K, Coull BM, Kidwell CS. Six-minute magnetic resonance imaging protocol for evaluation of acute ischemic stroke: pushing the boundaries. Stroke. 2014 Jul; 45(7):1985-91.
Nael K, Meshksar A, Ellingson B, Pirastehfar M, Salamon N, Finn P, Liebeskind DS, Villablanca JP. Combined low-dose contrast-enhanced MR angiography and perfusion for acute ischemic stroke at 3T: A more efficient stroke protocol. AJNR Am J Neuroradiol. 2014 Jun; 35(6):1078-84.
Meshksar A, Villablanca JP, Khan R, Carmody R, Coull B, Nael K. Role of EPI-FLAIR in patients with acute stroke: a comparative analysis with FLAIR. AJNR Am J Neuroradiol. 2014 May; 35(5):878-83.
Nael K, Meshksar A, Liebeskind DS, Coull BM, Krupinski EA, Villablanca JP. Quantitative analysis of hypoperfusion in acute stroke: arterial spin labeling versus dynamic susceptibility contrast. Stroke. 2013 Nov; 44(11):3090-6.
Khan R, Nael K, Erly W. Acute stroke imaging: what clinicians need to know. Am J Med. 2013 May; 126(5):379-86.
Nael K, Meshksar A, Liebeskind DS, Wang DJ, Ellingson BM, Salamon N, Villablanca JP, UCLA Stroke investigators. Periprocedural arterial spin labeling and dynamic susceptibility contrast perfusion in detection of cerebral blood flow in patients with acute ischemic syndrome. Stroke. 2013 Mar; 44(3):664-70.
Nael K, Moriarty JM, Finn JP. Low dose CE-MRA. Eur J Radiol. 2011 Oct; 80(1):2-8.
Nael K, Krishnam M, Ruehm SG, Michaely HJ, Laub G, Finn JP. Time-resolved MR angiography in the evaluation of central thoracic venous occlusive disease. AJR Am J Roentgenol. 2009 Jun; 192(6):1731-8.
Nael K, Kee ST, Solomon H, Katz SG. Endovascular management of central thoracic veno-occlusive diseases in hemodialysis patients: a single institutional experience in 69 consecutive patients. J Vasc Interv Radiol. 2009 Jan; 20(1):46-51.
Michaely HJ, Attenberger UI, Dietrich O, Schmitt P, Nael K, Kramer H, Reiser MF, Schoenberg SO, Walz M. Feasibility of gadofosveset-enhanced steady-state magnetic resonance angiography of the peripheral vessels at 3 Tesla with Dixon fat saturation. Invest Radiol. 2008 Sep; 43(9):635-41.
Nael K, Krishnam M, Nael A, Ton A, Ruehm SG, Finn JP. Peripheral contrast-enhanced MR angiography at 3.0T, improved spatial resolution and low dose contrast: initial clinical experience. Eur Radiol. 2008 Dec; 18(12):2893-900.
Fenchel M, Nael K, Seeger A, Kramer U, Saleh R, Miller S. Whole-body magnetic resonance angiography at 3.0 Tesla. Eur Radiol. 2008 Jul; 18(7):1473-83.
Nael K, Villablanca JP, Mossaz L, Pope W, Juncosa A, Laub G, Finn JP. 3-T contrast-enhanced MR angiography in evaluation of suspected intracranial aneurysm: comparison with MDCT angiography. AJR Am J Roentgenol. 2008 Feb; 190(2):389-95.
Michaely HJ, Kramer H, Dietrich O, Nael K, Lodemann KP, Reiser MF, Schoenberg SO. Intraindividual comparison of high-spatial-resolution abdominal MR angiography at 1.5 T and 3.0 T: initial experience. Radiology. 2007 Sep; 244(3):907-13.
Michaely HJ, Attenberger UI, Kramer H, Nael K, Reiser MF, Schoenberg SO. Abdominal and pelvic MR angiography. Magn Reson Imaging Clin N Am. 2007 Aug; 15(3):301-14, v-vi.
Nael K, Fenchel M, Saleh R, Finn JP. Cardiac MR imaging: new advances and role of 3T. Magn Reson Imaging Clin N Am. 2007 Aug; 15(3):291-300, v.
Fenchel M, Saleh R, Dinh H, Lee MH, Nael K, Krishnam M, Ruehm SG, Miller S, Child J, Finn JP. Juvenile and adult congenital heart disease: time-resolved 3D contrast-enhanced MR angiography. Radiology. 2007 Aug; 244(2):399-410.
Nael K, Fenchel M, Krishnam M, Finn JP, Laub G, Ruehm SG. 3.0 Tesla high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) of the pulmonary circulation: initial experience with a 32-channel phased array coil using a high relaxivity contrast agent. Invest Radiol. 2007 Jun; 42(6):392-8.
Fenchel M, Kramer U, Nael K, Miller S. Cardiac magnetic resonance imaging at 3.0 T. Top Magn Reson Imaging. 2007 Apr; 18(2):95-104.
Kramer U, Nael K, Fenchel M, Miller S. Magnetic resonance angiography of chest and abdomen at 3 T. Top Magn Reson Imaging. 2007 Apr; 18(2):105-15.
Nael K, Fenchel MC, Kramer U, Finn JP, Ruehm SG, Gruehm S. Whole-body contrast-enhanced magnetic resonance angiography: new advances at 3.0 T. Top Magn Reson Imaging. 2007 Apr; 18(2):127-34.
Nael K, Fenchel M, Krishnam M, Laub G, Finn JP, Ruehm SG. High-spatial-resolution whole-body MR angiography with high-acceleration parallel acquisition and 32-channel 3.0-T unit: initial experience. Radiology. 2007 Mar; 242(3):865-72.
Nael K, Ruehm SG, Michaely HJ, Saleh R, Lee M, Laub G, Finn JP. Multistation whole-body high-spatial-resolution MR angiography using a 32-channel MR system. AJR Am J Roentgenol. 2007 Feb; 188(2):529-39.
Nael K, Villablanca JP, Pope WB, McNamara TO, Laub G, Finn JP. Supraaortic arteries: contrast-enhanced MR angiography at 3.0 T--highly accelerated parallel acquisition for improved spatial resolution over an extended field of view. Radiology. 2007 Feb; 242(2):600-9.
Nael K, Saleh R, Nyborg GK, Fonseca CG, Weinmann HJ, Laub G, Finn JP. Pulmonary MR perfusion at 3.0 Tesla using a blood pool contrast agent: Initial results in a swine model. J Magn Reson Imaging. 2007 Jan; 25(1):66-72.
Michaely HJ, Nael K, Schoenberg SO, Finn JP, Oesingmann N, Lodemann KP, Reiser MF, Ruehm SG. Renal perfusion: comparison of saturation-recovery TurboFLASH measurements at 1.5T with saturation-recovery TurboFLASH and time-resolved echo-shared angiographic technique (TREAT) at 3.0T. J Magn Reson Imaging. 2006 Dec; 24(6):1413-9.
Villablanca JP, Nael K, Habibi R, Nael A, Laub G, Finn JP. 3 T contrast-enhanced magnetic resonance angiography for evaluation of the intracranial arteries: comparison with time-of-flight magnetic resonance angiography and multislice computed tomography angiography. Invest Radiol. 2006 Nov; 41(11):799-805.
Finn JP, Nael K, Deshpande V, Ratib O, Laub G. Cardiac MR imaging: state of the technology. Radiology. 2006 Nov; 241(2):338-54.
Nael K, Fenchel M, Salamon N, Duckwiler GR, Laub G, Finn JP, Villablanca JP. Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: initial results using highly accelerated parallel acquisition. Invest Radiol. 2006 Oct; 41(10):763-8.
Fenchel M, Nael K, Deshpande VS, Finn JP, Kramer U, Miller S, Ruehm S, Laub G. Renal magnetic resonance angiography at 3.0 Tesla using a 32-element phased-array coil system and parallel imaging in 2 directions. Invest Radiol. 2006 Sep; 41(9):697-703.
Fenchel M, Deshpande VS, Nael K, Finn JP, Miller S, Ruehm S, Laub G. Cardiac cine imaging at 3 Tesla: initial experience with a 32-element body-array coil. Invest Radiol. 2006 Aug; 41(8):601-8.
Nael K, Michaely HJ, Lee M, Goldin J, Laub G, Finn JP. Dynamic pulmonary perfusion and flow quantification with MR imaging, 3.0T vs. 1.5T: initial results. J Magn Reson Imaging. 2006 Aug; 24(2):333-9.
Nael K, Michaely HJ, Kramer U, Lee MH, Goldin J, Laub G, Finn JP. Pulmonary circulation: contrast-enhanced 3.0-T MR angiography--initial results. Radiology. 2006 Sep; 240(3):858-68.
Nael K, Saleh R, Lee M, McNamara T, Godinez SR, Laub G, Finn JP, Ruehm SG. High-spatial-resolution contrast-enhanced MR angiography of abdominal arteries with parallel acquisition at 3.0 T: initial experience in 32 patients. AJR Am J Roentgenol. 2006 Jul; 187(1):W77-85.
Fenchel M, Nael K, Ruehm S, Finn JP, Miller S, Laub G. Isotropic high spatial resolution magnetic resonance angiography of the supra-aortic arteries using two-dimensional parallel imaging (iPAT2) at 3 Tesla: a feasibility study. Invest Radiol. 2006 Jul; 41(7):545-52.
Michaely HJ, Dietrich O, Nael K, Weckbach S, Reiser MF, Schoenberg SO. MRA of abdominal vessels: technical advances. Eur Radiol. 2006 Aug; 16(8):1637-50.
Nael K, Ruehm SG, Michaely HJ, Pope W, Laub G, Finn JP, Villablanca JP. High spatial-resolution CE-MRA of the carotid circulation with parallel imaging: comparison of image quality between 2 different acceleration factors at 3.0 Tesla. Invest Radiol. 2006 Apr; 41(4):391-9.
Fenchel M, Nael K, Herget-Rosenthal S, Krishnam M, Ruehm SG. Magnetic resonance imaging of renal disease: recent developments and future applications. Nephron Clin Pract. 2006; 103(2):c37-44.
Michaely HJ, Nael K, Schoenberg SO, Laub G, Reiser MF, Finn JP, Ruehm SG. Analysis of cardiac function--comparison between 1.5 Tesla and 3.0 Tesla cardiac cine magnetic resonance imaging: preliminary experience. Invest Radiol. 2006 Feb; 41(2):133-40.
Kramer U, Nael K, Laub G, Nyborg GK, Fenchel M, Miller S, Claussen CD, Finn JP. High-resolution magnetic resonance angiography of the renal arteries using parallel imaging acquisition techniques at 3.0 T: initial experience. Invest Radiol. 2006 Feb; 41(2):125-32.
Nael K, Michaely HJ, Villablanca P, Salamon N, Laub G, Finn JP. Time-resolved contrast enhanced magnetic resonance angiography of the head and neck at 3.0 tesla: initial results. Invest Radiol. 2006 Feb; 41(2):116-24.
Nael K, Laub G, Finn JP. Three-dimensional contrast-enhanced MR angiography of the thoraco-abdominal vessels. Magn Reson Imaging Clin N Am. 2005 May; 13(2):359-80.