Myriam Chaumeil, PhD, recipient of 2013 Bruce Hasegawa Award
October 29, 2013
At the Department of Radiology and Biomedical Imaging’s 10th annual Research Symposium on October 29, 2013, Myriam Chaumeil, PhD was presented with the 2013 Bruce Hasegawa Award.
Dr. Chaumeil is a postdoctoral scholar working in the laboratory of Sabrina Ronen, PhD, where she applies innovative magnetic resonance techniques, such as hyperpolarized carbon-13 and contrast-enhanced imaging, to characterize brain tumors and their response to treatments. She earned her PhD in Medical Physics from the University of Paris XI, France.
In accepting the award, Chaumeil remarked: “I feel really lucky to have had the chance to work in this department with an amazing group of people, and to follow Professor Hasegawa’s footsteps in developing new imaging techniques, such as hyperpolarized 13-C MR spectroscopy. I would like to thank all my colleagues from the Surbeck lab and QB3 for their help and friendship. I would like to also give special thanks to my mentor and PI Sabrina Ronen for her continuous support over the last five years. And finally, I would like to thank the Symposium Committee as well as Bruce Hasegawa’s friends and family for this generous award. I feel really honored.”
The Bruce Hasegawa Award recognizes a radiology and biomedical imaging graduate student or postdoctoral scholar annually. It is generously funded by Hasegawa’s childhood friend, Dr. Gordon Honda.
UCSF is the only fibroid treatment center in Northern California to have completed a research study of the latest, most advanced, FDA approved procedure with excellent results. These are minimally invasive procedures which may help women avoid invasive surgeries such as hysterectomy or myomectomy.
With 28,000 attendees, the 2013 Bay Area Science Festival was a huge success. On Saturday, November 2nd, children and adults were scattered throughout the AT&T baseball field enjoying some fun in the sun, and a stadium full of science. With the many different exciting exhibits, games, and entertainment, no one wanted to go home when it came to closing time.
The Department of Radiology and Biomedical Imaging had a booth there with many interactive activities to drum up excitement about radiology. We created a game called, “Match That Bone”, where we showed kids and parents different x-ray images on an iPad. Next, we had them try and match those images to a skeleton model. Our booth also featured a power point slide highlighting the department’s ten subspecialties. We also played an MRI video, a video of Dr. Bill Dillon explaining steps to becoming a radiologist, and a video of Dr. Brett Elicker talking about radiation exposure.
This is the first year the Department of Radiology and Biomedical Imaging has participated in the science festival, and we hope to come back every year. Especially, when many parents and children were asking, “What is radiology?”. It is a compliment to have people ask these types of questions. It gives us a chance to interact with them, share our experiences, and spread our knowledge.
We personally would like to thank everyone who volunteered to help make our booth a success:
Thank you Dr. Bob Kerlan and Kathy Knoerl, Operations Director Radiology, for volunteering and showing your support.
Thank you Matt Eltgroth, MD, Nick Burris, MD, Mariam Aboian, MD, Kevin Koo, MD, Nancy Benedetti, MD, Hriday Shah, MD, Marcel Brus-Ramer, MD, PhD, Craig Devincent, Ben Mow, Rebecca Galagaran, Javier Villanueva-Meyer, MD, and Vignesh Arasu, MD for sharing your knowledge on radiology.
Lastly, thank you Mercedes Curutchet and Etay Ziv, MD for making the MRI video.
This two-day workshop is sponsored by the Department of Radiology and Biomedical Imaging, UCSF, and the international Study Group for XTrEme‐Ct in RA (SPECTRA). The SPECTRA group is an international consortium aiming to investigate the validity, reliability, and responsiveness of an emerging imaging modality, high‐resolution peripheral quantitative computed tomography (HR‐pQCT), as a biomarker for joint damage in inflammatory arthritis. The participants include clinicians and researchers from the United States, Canada, Germany, France, the Netherlands, Denmark, and Hong Kong.
The workshop will have keynote presentations reviewing imaging applications in rheumatoid arthritis, from the perspectives of rheumatologists as well as radiologists, followed by indepth discussion on the technical aspects of HR-pQCT, standardization of the evaluation of bone erosions in RA using HR-pQCT, quantitative analysis of joint shape and bone structure, and multi-modality studies in RA using HR-pQCT, MRI and other techniques.
The workshop is free and open to all clinicians, researchers and industrial investigators. For registration and other more information, please contact Rukayah Abdolcader at firstname.lastname@example.org or (415) 514-8270.
The Department of Radiology and Biomedical Imaging’s Annual Research Symposium has grown in scope each year, serving as a touchstone for the array of research performed in the department. The Tenth Annual Imaging Research Symposium will “provide a snapshot of the diversity and depth of the excellence in research in our department" according to Sharmila Majumdar, PhD, Vice-Chair of Research. It brings the achievements of high school, college, medical and graduate students, post-docs, fellows, residents and faculty to the forefront at oral presentations and a large poster session.
Scheduled for October 29, 2013, the symposium is open to the UCSF and scientific communities. The Imaging Research Symposium will begin at 1:00 PM in Cole Hall at UCSF’s Parnasssus Campus and will feature brief oral presentations, which will cover a variety of topics and approaches to imaging research. At 4:30 PM, a poster session and presentation of the annual Bruce Hasegawa Award will be held in the City Lights and Golden Gate rooms at Millberry Union.
Amyloid Imaging: A “Game Changer” in the Diagnosis of Alzheimer’s Disease
September 17, 2013
Amyloid imaging has been used extensively in research studies of Alzheimer’s disease (AD) and aging since 2004. Since the earliest days of this technology, UCSF has been at the forefront of amyloid imaging research. The UCSF-based Alzheimer’s Disease Neuroimaging Initiative (ADNI) is a large, multi-site study applying amyloid imaging and other imaging modalities and biological markers to study the natural history of AD, with the goal of utilizing imaging and other disease markers to measure the efficacy of new treatments.
Sarah Nelson, PhD Using sugar to diagnose & assess prostate cancer tumors
September 11, 2013
A recent publication describes the first in-man study that has been performed at UCSF using new imaging technology. The results have shown that it is safe in humans and that it effectively detects tumors in patients with prostate cancer. This lays the groundwork for the use of this technology to diagnose a variety of cancers and to track treatment noninvasively, without repeated biopsies.
Dr. Mukherjee received his undergraduate degree in Computer Science from Yale University. He received his M.D at Cornell University and his Ph.D. in neuroscience at Rockefeller University. After completing a radiology residency and neuroradiology fellowship at Washington University, St. Louis, Dr. Mukherjee joined our faculty at UCSF where he has excelled in imaging research focused on cognitive neuroscience. Dr. Mukherjee is an internationally recognized expert in imaging of structural and functional brain connectivity, including the human connectome as well as imaging of traumatic brain injury. He is one of the world’s leading experts on diffusion MRI and tractography, having published dozens of papers in this field, and was an expert panelist of the Institute of Medicine (IOM) of the National Academy of Sciences in August to develop standards for diffusion MRI for both scientific and clinical applications. Recent peer-reviewed publications from his laboratory include original research papers on the human structural connectome as well as functional connectivity imaging of traumatic brain injury (TBI) with magnetoencephalography (MEG).
Dr. Mukherjee has established a successful research program in advanced neuroimaging of mild TBI (which accounts for the vast majority of TBI in the military population), with several of the most highly cited papers in the TBI literature over the past 5 years and several more currently in the publication pipeline (including one on resting state MEG of TBI that is featured on the cover of the June 2013 issue of the Journal of Neurosurgery). His research program is funded by grants from the NIH, the Department of Defense, and the Brain Trauma Foundation, with past funding from the Dana Foundation and the McDonnell Foundation. He has served as the Neuroimaging Core Director and one of the PIs for a current $18 million NIH U01 multi-center grant proposal to create an International TBI Research collaboration. The study of TBI and post-traumatic stress disorder (PTSD) in veterans will be a natural new direction for Dr. Mukherjee's research program.
As a practicing clinical neuroradiologist, Dr. Mukherjee is well qualified to oversee translation of research performed at the CIND to routine use in the reading room and other clinical arenas such as image guidance in the operating room. His contributions at UCSF include developing high angular resolution diffusion imaging (HARDI) and tractography methods that are used on an almost daily basis at UCSF for presurgical white matter mapping, and (2) creating a thriving clinical functional MRI service at UCSF. Quantitative volumetrics of neurodegenerative diseases, an area of particular strength for the CIND, is perhaps the most promising area for current clinical translation to the reading room. The integration of structural MRI, physiologic MRI and metabolic/molecular imaging using FDG-PET and amyloid PET will be a goal for translational research at the CIND. Pratik is well qualified to accelerate research in multimodal imaging, with his expertise in machine learning techniques that he has employed with increasing sophistication in recent scientific publications.
As a UCSF faculty member for more than a decade, Dr. Mukherjee has developed extensive clinical and research collaborations with the faculty of departments such as Radiology, Bioengineering, Neurosurgery, Neurology and Psychiatry. He will leverage these ties to increase alliances between CIND and non-SFVAMC UCSF faculty for joint research initiatives. This will also allow non-SFVAMC UCSF faculty to utilize unique CIND resources, such as the research Siemens 3T and 7T scanners, thereby contributing to the success of the CIND. CIND investigators will also benefit from UCSF campus resources such as the MEG scanner, the forthcoming MR-PET system and the Bioengineering computing cluster.
Again I want to express my appreciation to Michael Weiner, MD, for his excellent leadership of CIND for so many years. Please join me in congratulating Dr. Mukherjee and wish him success in his new role.