Vascular Imaging Research Center

The VIRC investigates the assessment and treatment of vascular disease. Studies are directed at imaging of the vascular lumen and atherosclerotic disease of the vessel wall. Newer treatment modalities under investigation include the evaluation of the performance of bifurcated stent-grafts used in the treatment of aortic disease. In addition, investigators are interested in numerical and flow model studies of hemodynamics. Lab collaborators include imaging scientists, radiologists, and surgeons, and there is extensive interaction with theoretical and experimental engineers at UC Berkeley. MR imaging studies are performed on a state-of-the-art whole body scanner. Other equipment for imaging studies include ultrasound scanners, a laser Doppler velocimeter for high resolution fluid velocity measurements, and a wide variety of physiologically realistic flow models. Computational resources include high-speed computer workstations and computational code for fluid dynamics modeling. The center also has workstations for postprocessing three-dimensional data sets including stereoscopic presentation with depth encoding. 

Publications

  • Jou LD, Rapp J, Saloner D. Transport of Contrast agents in contrast-enhanced magnetic resonance angiography. J Magn Reson Imaging 2004; 22:495-504.
  • Jou LD, Quick CM, Young WL, Lawton MT, Higashida R, Martin A, Saloner D. Computation approach to quantifying hemodynamic forces in giant cerebral aneurysms. Am J Neuroradiol; 2003; 24:1804-10.
  • Rapp JH, Saloner D. Current status of carotid imaging by MRA. Cardiovasc Surg 2003; 11:445-7.
  • Rapp JH, Pan XM, Yu B, Swanson R, Higashida R, Simpson P, Saloner D. Cerebral ischemia and infarction from atheroemboli. Stroke 2003; 64A:197-206.
  • Townsend TC, Saloner D, Pan XM, Rapp JH. Contrast material-enhanced MRA overestimates severity of carotid stenosis, compared with 3D time-of-flight MRA. J Vasc Surg 2003; 38:36-40.
  • Yu B, Pan XM, Saloner D, Troyer A, Rapp JH. Double-lumen carotid plaque: a morbid configuration. J Vasc Surg 2003; 37:1314-7.
  • Saeed M, Saloner D. Discrimination of myocardial acute and chronic (scar) infarctions on delayed contrast enhanced MRI using intravascular MR contrast media. JACC 2006;48:1961-1968
  • Wintermark, M, Tan J, Rapp, J.H. and Saloner D. Unmasking Complicated Atherosclerotic Plaques on Carotid MR-Angiography: A Report of Three Cases J. Vasc. Surg 2006 44, 884-887
  • Acevedo-Bolton G, Jou LD, Dispensa BP, Lawton MT, Higashida RT, Martin AJ, Young WL, Saloner D. Estimating the hemodynamic impact of interventional treatments of aneurysms: Numerical simulation with experimental validation: Technical case report. Neurosurgery 2006;59:E429-430
  • Saloner D., Acevedo-Bolton G, Wintermark M, and Rapp JH. MRI of Geometric and Compositional Features of Vulnerable Carotid Plaque. Stroke 2007; 38: 637-641.